The perfect solution of the scale-up of your cell culturing or microbial bioprocess

The models in the F2 series are the perfect solution for all those seeking for their first Steam In Place (SIP) stainless steel bioreactor/ fermenter for the scaling up of their bioprocesses and for small production applications. They are available in working volumes from 10 to 30 L.

THE REFERENCE IN THE MARKET
With a professional design and construction, which makes it the reference in the market, it integrates many extraordinary details to offer a user-friendly experience, ready to be easily integrated into your facilities.

PROCESS KNOWLEDGE & CONTROL
Providing the possibility to integrate a complete range of instrumentation and actuators, and allowing all kinds of associated control strategies helps you to better understand and improve your processes.
Example of instruments which can be added beyond the standard configuration are: Pressure, Optical Density, Viable Cells, Dissolved CO2, Exhaust gas composition, Redox, Weight and many others.
Most of these instruments have a corresponding MARTA SW module. These specific SW modules allow the user to select parameters as part of your control strategies and gives additional calculated information (e.g. OTR or OUR) in real time.

INTEGRATED CIP & SIP
The F2 can be delivered with integrated utilities (SIP and CIP) to help you to start your journey SIP Bioreactors in an easy way and with a minimal investment.
All in the same frame, with no extra-footprint. All controlled from our control SW MARTA with specific screens for complete control and programming of your Sterilisation and Cleaning In Place Cycle.
For the CIP recipes can be created and saved to allow for standardisation and productivity.

GMP DESIGNED, BUILT & QUALIFIED
As all BIONET equipment and projects the F2 can be designed, built and qualified under GMP guidelines to allow the validation of your processes.
Our GMP approach is structured so it can be adapted to your specific project and regulatory needs. The upgrade from a standard unit to a GMP one will affect many issues on the design and construction:
Technologies, Calibrations, Documentation, Qualification and SW (including ER under CFR 21 c11).
DQ, IQ & OQ

MARTA CONTROL SOFTWARE FOR BIOPROCESSING
MARTA is the Automation SW which comes installed in the F2 units. These models have off-the-shelve solutions for Cell Culture, Fermentation which can be expanded with additional modules for local SIP and CIP, new instrumentation or advanced gassing or dosing control.